Innovation in oncology has always moved quickly, but the current wave of highly personalised therapies is forcing healthcare systems to confront a more difficult question than ever before: not just can we develop these treatments, but how do we make them accessible in practice? A recent article in Value & Outcomes Spotlight by ISPOR explores this challenge through the lens of individualized neoantigen therapies (INTs), a promising new class of cancer treatments designed specifically for each...

Water, sanitation, and hygiene (WASH) are fundamental human rights and essential components to achieving the 2030 Sustainable Development Goals (SDGs), including SDG3: Good Health and Well-being and SDG6: Clean Water and Sanitation . However, globally, 2.2 billion people still do not have safely managed drinking water services, 4.2 billion people lack access to safely managed sanitation services, and 3 billion lack basic handwashing facilities . The significant lack of WASH infrastructure...

Some mental health risk factors disproportionately affect people who are defined as female at birth. These include pressures created by women’s multiple roles, socially constructed differences related to status and power, gender discrimination, associated factors related to the pay gap, domestic violence and sexual abuse . In research terms, more is known about the differences between those assigned male or female at birth in some conditions (schizophrenia and depression) than others. There...